Title : Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice.

Pub. Date : 2006 Jan 15

PMID : 16424025






1 Functional Relationships(s)
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1 This approach allowed us to verify the involvement of the Tcl1/Akt/mTOR biochemical pathway in the disease by testing the ability of a specific pharmacologic agent, rapamycin, to slow CLL. Sirolimus mechanistic target of rapamycin kinase Mus musculus