Title : Influence of pentoxifylline on natural cytotoxicity and expression of granzymes and PI-9, a specific granzyme B inhibitor.

Pub. Date : 2006 Jan

PMID : 16328022






2 Functional Relationships(s)
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Protein Name
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1 In this study, we show that PTX inhibits expression of granzyme A in human leukocytes probably due to suppression of phosphodiesterase activity. Pentoxifylline granzyme A Homo sapiens
2 Altogether, PTX inhibits natural cytotoxicity affecting mainly effector but not target cells and in case of the effector cells, besides previously reported mechanisms, it can also inhibit granzyme A expression. Pentoxifylline granzyme A Homo sapiens