Pub. Date : 2005 Aug 11
PMID : 16078853
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mechanism of poly(acrylic acid) acceleration of antithrombin inhibition of thrombin: implications for the design of novel heparin mimics. | carbopol 940 | serpin family C member 1 | Homo sapiens |
| 2 | Mechanism of poly(acrylic acid) acceleration of antithrombin inhibition of thrombin: implications for the design of novel heparin mimics. | carbopol 940 | coagulation factor II, thrombin | Homo sapiens |
| 3 | Our recent study of the antithrombin-activating properties of a carboxylic acid-based polymer, poly(acrylic acid) (PAA), demonstrated a surprisingly high acceleration in thrombin inhibition (Monien, B. H.; Desai, U. R. J. Med. | carbopol 940 | serpin family C member 1 | Homo sapiens |
| 4 | Our recent study of the antithrombin-activating properties of a carboxylic acid-based polymer, poly(acrylic acid) (PAA), demonstrated a surprisingly high acceleration in thrombin inhibition (Monien, B. H.; Desai, U. R. J. Med. | carbopol 940 | coagulation factor II, thrombin | Homo sapiens |
| 5 | Our recent study of the antithrombin-activating properties of a carboxylic acid-based polymer, poly(acrylic acid) (PAA), demonstrated a surprisingly high acceleration in thrombin inhibition (Monien, B. H.; Desai, U. R. J. Med. | carbopol 940 | serpin family C member 1 | Homo sapiens |
| 6 | Our recent study of the antithrombin-activating properties of a carboxylic acid-based polymer, poly(acrylic acid) (PAA), demonstrated a surprisingly high acceleration in thrombin inhibition (Monien, B. H.; Desai, U. R. J. Med. | carbopol 940 | coagulation factor II, thrombin | Homo sapiens |
| 7 | Competitive binding studies with low-affinity heparin and a heparin tetrasaccharide suggest that PAA binds antithrombin in both the pentasaccharide- and the extended heparin-binding sites, and these results are corroborated by molecular modeling. | carbopol 940 | serpin family C member 1 | Homo sapiens |
| 8 | A bell-shaped profile of the observed rate constant for antithrombin inhibition of thrombin as a function of PAA concentration was observed, suggesting that inhibition proceeds through the "bridging" mechanism. | carbopol 940 | serpin family C member 1 | Homo sapiens |
| 9 | A bell-shaped profile of the observed rate constant for antithrombin inhibition of thrombin as a function of PAA concentration was observed, suggesting that inhibition proceeds through the "bridging" mechanism. | carbopol 940 | coagulation factor II, thrombin | Homo sapiens |