Pub. Date : 2005 Nov 1
PMID : 16043163
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: The level of BK(Ca) alpha subunit tyrosine phosphorylation was increased in a time-dependent manner following hemorrhagic shock, which was mediated by protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTP). | Tyrosine | protein tyrosine phosphatase, non-receptor type 1 | Rattus norvegicus |
| 2 | RESULTS: The level of BK(Ca) alpha subunit tyrosine phosphorylation was increased in a time-dependent manner following hemorrhagic shock, which was mediated by protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTP). | Tyrosine | protein tyrosine phosphatase, non-receptor type 1 | Rattus norvegicus |
| 3 | The activation of VSMC BK(Ca) following hemorrhagic shock was inhibited by genistein (2x10(-5) mol/L), the permeable isoflavone PTK inhibitor, and was potentiated by the PTP inhibitor sodium orthovanadate (Na(3)VO(4), 10(-3) mol/L). | vsmc bk | protein tyrosine phosphatase, non-receptor type 1 | Rattus norvegicus |
| 4 | The activation of VSMC BK(Ca) following hemorrhagic shock was inhibited by genistein (2x10(-5) mol/L), the permeable isoflavone PTK inhibitor, and was potentiated by the PTP inhibitor sodium orthovanadate (Na(3)VO(4), 10(-3) mol/L). | Genistein | protein tyrosine phosphatase, non-receptor type 1 | Rattus norvegicus |
| 5 | The activation of VSMC BK(Ca) following hemorrhagic shock was inhibited by genistein (2x10(-5) mol/L), the permeable isoflavone PTK inhibitor, and was potentiated by the PTP inhibitor sodium orthovanadate (Na(3)VO(4), 10(-3) mol/L). | Sodium orthovanadate | protein tyrosine phosphatase, non-receptor type 1 | Rattus norvegicus |
| 6 | CONCLUSION: The tyrosine residues of BK(Ca) alpha subunit of SMA were phosphorylated following hemorrhagic shock, which was regulated by PTK and PTP and appeared to be related to the activation of BK(Ca) and the development of vascular hyporesponsiveness following hemorrhagic shock. | Tyrosine | protein tyrosine phosphatase, non-receptor type 1 | Rattus norvegicus |