Pub. Date : 2005 Jul
PMID : 15978256
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Troglitazone significantly increased NO production and iNOS expression after 24hr in a dose-and PPARgamma-dependent manner. | Troglitazone | nitric oxide synthase 2 | Bos taurus |
| 2 | Elevation of D-glucose, but not L-glucose, from 5.5 to 30 mm for 24 hr decreased NO production, but co-treatment with troglitazone reversed high glucose-induced inhibition of NO production as well as iNOS expression. | Troglitazone | nitric oxide synthase 2 | Bos taurus |
| 3 | In conclusion, high glucose inhibits iNOS expression and subsequently NO synthesis in cultured bovine retinal pericytes, and troglitazone restores the NO production. | Glucose | nitric oxide synthase 2 | Bos taurus |