Title : The acute box cis-element in human heavy ferritin mRNA 5'-untranslated region is a unique translation enhancer that binds poly(C)-binding proteins.

Pub. Date : 2005 Aug 26

PMID : 15967798






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Labeled AB transcripts formed specific complexes with hepatoma cell extracts that contained the poly(C)-binding proteins, iso-alphaCP1 and -alphaCP2, which have well defined roles as translation regulators. Poly C poly(rC) binding protein 1 Homo sapiens
2 Iron influx increased the association of alphaCP1 with ferritin mRNA and decreased the alphaCP2-ferritin mRNA interaction, whereas IL-1beta reduced the association of alphaCP1 and alphaCP2 with H-ferritin mRNA. Iron poly(rC) binding protein 1 Homo sapiens