Title : Intracellular calcium release and cardiac disease.

Pub. Date : 2005

PMID : 15709953






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 These regulatory proteins include calstabin1/calstabin2 (FKBP12/FKBP12.6), a 12/12.6 kDa subunit that stabilizes the closed state of the channel and prevents aberrant calcium leak from the SR. Kinases and phosphatases are targeted to RyR2 channels and modulate RyR2 function in response to extracellular signals. Calcium FKBP prolyl isomerase 1B Homo sapiens
2 These regulatory proteins include calstabin1/calstabin2 (FKBP12/FKBP12.6), a 12/12.6 kDa subunit that stabilizes the closed state of the channel and prevents aberrant calcium leak from the SR. Kinases and phosphatases are targeted to RyR2 channels and modulate RyR2 function in response to extracellular signals. Calcium FKBP prolyl isomerase 1B Homo sapiens