Title : Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival.

Pub. Date : 2005 Jun 1

PMID : 15705789






1 Functional Relationships(s)
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1 In Akt-transformed leukemic cells, tumor growth can be inhibited by the mTOR inhibitor rapamycin, and clinical trials of rapamycin analogs for the treatment of leukemia are under way. Sirolimus mechanistic target of rapamycin kinase Mus musculus