Pub. Date : 2004 Oct
PMID : 15454728
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CYP3A4 expression is highly variable and is induced by numerous compounds of exogenous and endogenous origin, including elevated concentrations of secondary bile acids via the pregnane X receptor (PXR). | Bile Acids and Salts | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |
| 2 | CYP3A4 expression is highly variable and is induced by numerous compounds of exogenous and endogenous origin, including elevated concentrations of secondary bile acids via the pregnane X receptor (PXR). | Bile Acids and Salts | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |
| 3 | Thus, whereas elevated concentrations of precursors of bile acids and secondary bile acids induce CYP3A via PXR, primary bile acids can modulate the expression of CYP3A via FXR. | Bile Acids and Salts | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |
| 4 | Thus, whereas elevated concentrations of precursors of bile acids and secondary bile acids induce CYP3A via PXR, primary bile acids can modulate the expression of CYP3A via FXR. | Bile Acids and Salts | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |
| 5 | Thus, whereas elevated concentrations of precursors of bile acids and secondary bile acids induce CYP3A via PXR, primary bile acids can modulate the expression of CYP3A via FXR. | Bile Acids and Salts | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |