Pub. Date : 2004 Nov 26
PMID : 15377673
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PI3K inhibition by LY294002 showed an increase in NAG-1 protein and mRNA expression, and 1l-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate (AKT inhibitor) also induced NAG-1 expression. | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | growth differentiation factor 15 | Homo sapiens |
| 2 | PI3K inhibition by LY294002 showed an increase in NAG-1 protein and mRNA expression, and 1l-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate (AKT inhibitor) also induced NAG-1 expression. | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | growth differentiation factor 15 | Homo sapiens |
| 3 | PI3K inhibition by LY294002 showed an increase in NAG-1 protein and mRNA expression, and 1l-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate (AKT inhibitor) also induced NAG-1 expression. | 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate | growth differentiation factor 15 | Homo sapiens |
| 4 | Inhibition of GSK-3beta, which is negatively regulated by AKT, using AR-A014418 and lithium chloride completely abolished LY294002-induced NAG-1 expression as well as the NAG-1 promoter activity. | Lithium Chloride | growth differentiation factor 15 | Homo sapiens |
| 5 | Inhibition of GSK-3beta, which is negatively regulated by AKT, using AR-A014418 and lithium chloride completely abolished LY294002-induced NAG-1 expression as well as the NAG-1 promoter activity. | Lithium Chloride | growth differentiation factor 15 | Homo sapiens |
| 6 | Inhibition of GSK-3beta, which is negatively regulated by AKT, using AR-A014418 and lithium chloride completely abolished LY294002-induced NAG-1 expression as well as the NAG-1 promoter activity. | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | growth differentiation factor 15 | Homo sapiens |
| 7 | Furthermore, the down-regulation of GSK-3 gene using small interference RNA resulted in a decline of the NAG-1 expression in the presence of LY294002. | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | growth differentiation factor 15 | Homo sapiens |