Title : Persistent HIF-1alpha activation in gut ischemia/reperfusion injury: potential role of bacteria and lipopolysaccharide.

Pub. Date : 2004 Sep

PMID : 15316398






1 Functional Relationships(s)
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1 Because hypoxia-inducible factor (HIF-1), a transcription factor composed of oxygen-labile HIF-1alpha and constitutive HIF-1beta subunits, regulates the physiologic/pathophysiologic response to hypoxia and ischemia, we examined the HIF-1 response in two rat models of gut ischemia-reperfusion. Oxygen hypoxia inducible factor 1 subunit alpha Rattus norvegicus