Title : TRPM7: channeling the future of cellular magnesium homeostasis?

Pub. Date : 2004 May 11

PMID : 15150423






9 Functional Relationships(s)
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1 TRPM7: channeling the future of cellular magnesium homeostasis? Magnesium transient receptor potential cation channel subfamily M member 7 Homo sapiens
2 A recent paper by Schmitz and colleagues provides persuasive evidence that the ion channel transient receptor potential melastatin 7 (TRPM7) may be the long-sought regulator of magnesium (Mg) homeostasis in mammalian cells. Magnesium transient receptor potential cation channel subfamily M member 7 Homo sapiens
3 A recent paper by Schmitz and colleagues provides persuasive evidence that the ion channel transient receptor potential melastatin 7 (TRPM7) may be the long-sought regulator of magnesium (Mg) homeostasis in mammalian cells. Magnesium transient receptor potential cation channel subfamily M member 7 Homo sapiens
4 A recent paper by Schmitz and colleagues provides persuasive evidence that the ion channel transient receptor potential melastatin 7 (TRPM7) may be the long-sought regulator of magnesium (Mg) homeostasis in mammalian cells. Magnesium transient receptor potential cation channel subfamily M member 7 Homo sapiens
5 A recent paper by Schmitz and colleagues provides persuasive evidence that the ion channel transient receptor potential melastatin 7 (TRPM7) may be the long-sought regulator of magnesium (Mg) homeostasis in mammalian cells. Magnesium transient receptor potential cation channel subfamily M member 7 Homo sapiens
6 However, these studies introduce an exciting new twist into our understanding of Mg homeostasis; TRPM7 facilitates Mg entry into the cell, whereas other putative Mg transporters apparently operate in the opposite direction. Magnesium transient receptor potential cation channel subfamily M member 7 Homo sapiens
7 However, these studies introduce an exciting new twist into our understanding of Mg homeostasis; TRPM7 facilitates Mg entry into the cell, whereas other putative Mg transporters apparently operate in the opposite direction. Magnesium transient receptor potential cation channel subfamily M member 7 Homo sapiens
8 TRPM7 genetics are well in hand, its regulation by intracellular free Mg2+ unravels the mechanisms of regulatory feedback loops, and its kinase domain modulates its sensitivity to free Mg2+. magnesium ion transient receptor potential cation channel subfamily M member 7 Homo sapiens
9 TRPM7 genetics are well in hand, its regulation by intracellular free Mg2+ unravels the mechanisms of regulatory feedback loops, and its kinase domain modulates its sensitivity to free Mg2+. magnesium ion transient receptor potential cation channel subfamily M member 7 Homo sapiens