Title : Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2.

Pub. Date : 2004 Apr 9

PMID : 15073377






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A derivative of 1,4-benzothiazepine (JTV519) increased the affinity of calstabin2 for RyR2, which stabilized the closed state of RyR2 and prevented the Ca2+ leak that triggers arrhythmias. 1,4-Benzothiazepine FKBP prolyl isomerase 1B Homo sapiens