Title : Combination of rapamycin and protein tyrosine kinase (PTK) inhibitors for the treatment of leukemias caused by oncogenic PTKs.

Pub. Date : 2004 Mar 2

PMID : 14976243






1 Functional Relationships(s)
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1 Here, we report that the mTOR inhibitor rapamycin synergizes with Imatinib against BCR/ABL-transformed myeloid and lymphoid cells and increases survival in a murine CML model. Imatinib Mesylate mechanistic target of rapamycin kinase Mus musculus