Title : Methylxanthine-induced inhibition of the antigen- and superantigen-specific activation of T and B lymphocytes.

Pub. Date : 1992 Nov-Dec

PMID : 1478854






2 Functional Relationships(s)
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1 Both PTX and caffeine significantly inhibited mitogen- and SEB-induced proliferation by murine spleen cells, SEB- and antigen-induced proliferation and lymphokine secretion by murine Th1 and Th2 clones, and the generation of antigen-specific antibody producing murine spleen cells. Pentoxifylline heart and neural crest derivatives expressed 2 Mus musculus
2 Both PTX and caffeine significantly inhibited mitogen- and SEB-induced proliferation by murine spleen cells, SEB- and antigen-induced proliferation and lymphokine secretion by murine Th1 and Th2 clones, and the generation of antigen-specific antibody producing murine spleen cells. Caffeine heart and neural crest derivatives expressed 2 Mus musculus