Title : Protein kinase A phosphorylation at serine-2808 of the cardiac Ca2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6).

Pub. Date : 2004 Mar 5

PMID : 14715536






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Dissociation of FKBP12.6 from the cardiac Ca2+-release channel (RyR2) as a consequence of protein kinase A (PKA) hyperphosphorylation of RyR2 at a single amino acid residue, serine-2808, has been proposed as an important mechanism underlying cardiac dysfunction in heart failure. Serine FKBP prolyl isomerase 1B Homo sapiens
2 We found that FKBP12.6 can bind to both the serine-2808 phosphorylated and nonphosphorylated forms of RyR2. Serine FKBP prolyl isomerase 1B Homo sapiens