Title : Amifostine induces anaerobic metabolism and hypoxia-inducible factor 1 alpha.

Pub. Date : 2004 Jan

PMID : 14574457






2 Functional Relationships(s)
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1 In vivo experiments with Wistar rats were performed in order to assess immunohistochemically changes in the intracellular accumulation of HIF1 alpha induced by amifostine (200 mg/kg). Amifostine hypoxia inducible factor 1 subunit alpha Rattus norvegicus
2 In Wistar rats administration of amifostine resulted in increased HIF1 alpha accumulation in normal tissues. Amifostine hypoxia inducible factor 1 subunit alpha Rattus norvegicus