Title : Molecular basis of ion selectivity, block, and rectification of the inward rectifier Kir3.1/Kir3.4 K(+) channel.

Pub. Date : 2003 Dec 5

PMID : 14504281






2 Functional Relationships(s)
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1 We show that mutation of charged glutamate and arginine residues behind the selectivity filter in the Kir3.1/Kir3.4 K+ channel reduces or abolishes K+ selectivity, comparable with previously reported effects in the Kir2.1 K+ channel. Glutamic Acid potassium inwardly rectifying channel subfamily J member 3 Homo sapiens
2 We show that mutation of charged glutamate and arginine residues behind the selectivity filter in the Kir3.1/Kir3.4 K+ channel reduces or abolishes K+ selectivity, comparable with previously reported effects in the Kir2.1 K+ channel. Arginine potassium inwardly rectifying channel subfamily J member 3 Homo sapiens