Title : Cytochrome P-450 arachidonic acid epoxygenase. Regulatory control of the renal epoxygenase by dietary salt loading.

Pub. Date : 1992 Oct 25

PMID : 1400482






3 Functional Relationships(s)
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1 Immunoblotting studies demonstrated that dietary salt induced marked increases in the concentration of a cytochrome P-450 isoform(s) recognized by polyclonal antibodies raised against human liver cytochrome P-450 2C10 or rat liver cytochrome P-450 2C11. Salts cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus
2 Comparisons of the stereochemical selectivity of the induced and non-induced microsomal epoxygenase(s) with that of purified rat liver cytochrome P-450 2C11 suggest that the salt-induced protein(s) is catalytically and structurally different from liver cytochrome P-450 2C11. Salts cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus
3 Comparisons of the stereochemical selectivity of the induced and non-induced microsomal epoxygenase(s) with that of purified rat liver cytochrome P-450 2C11 suggest that the salt-induced protein(s) is catalytically and structurally different from liver cytochrome P-450 2C11. Salts cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus