Pub. Date : 1992 Sep 1
PMID : 1380889
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Influence of tamoxifen on plasma levels of insulin-like growth factor I and insulin-like growth factor binding protein I in breast cancer patients. | Tamoxifen | insulin like growth factor 1 | Homo sapiens |
| 2 | Influence of tamoxifen on plasma levels of insulin-like growth factor I and insulin-like growth factor binding protein I in breast cancer patients. | Tamoxifen | insulin | Homo sapiens |
| 3 | Tamoxifen suppressed total plasma IGF-I by a mean of 28.5% (P less than 0.001) but elevated plasma IGFBP-I by a mean value of 78% (P less than 0.001). | Tamoxifen | insulin like growth factor 1 | Homo sapiens |
| 4 | These findings suggest that tamoxifen exerts its influence on plasma IGF-I and IGFBP-I by mechanisms other than those known to regulate the plasma levels of these peptides, primarily growth hormone and insulin, respectively. | Tamoxifen | insulin like growth factor 1 | Homo sapiens |
| 5 | These findings suggest that tamoxifen exerts its influence on plasma IGF-I and IGFBP-I by mechanisms other than those known to regulate the plasma levels of these peptides, primarily growth hormone and insulin, respectively. | Tamoxifen | insulin | Homo sapiens |
| 6 | A dual effect suppressing plasma IGF-I and elevating plasma IGFBP-I suggests that tamoxifen may have a significant influence on endocrine and possibly paracrine delivery of IGF-I to breast cancer cells in vivo. | Tamoxifen | insulin like growth factor 1 | Homo sapiens |
| 7 | A dual effect suppressing plasma IGF-I and elevating plasma IGFBP-I suggests that tamoxifen may have a significant influence on endocrine and possibly paracrine delivery of IGF-I to breast cancer cells in vivo. | Tamoxifen | insulin like growth factor 1 | Homo sapiens |