Pub. Date : 2003 Oct
PMID : 13678671
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Denervation and repeated L-DOPA induce a coordinate expression of the transcription factor NGFI-B in striatal projection pathways in hemi-parkinsonian rats. | Levodopa | nuclear receptor subfamily 4, group A, member 1 | Rattus norvegicus |
| 2 | In this study, we have investigated the effects of denervation and repeated L-DOPA administration on the expression of the nuclear receptor nerve growth factor inducible-B (NGFI-B) in striatal output pathways of unilaterally 6-OHDA-lesioned rats. | Levodopa | nuclear receptor subfamily 4, group A, member 1 | Rattus norvegicus |
| 3 | In this study, we have investigated the effects of denervation and repeated L-DOPA administration on the expression of the nuclear receptor nerve growth factor inducible-B (NGFI-B) in striatal output pathways of unilaterally 6-OHDA-lesioned rats. | Oxidopamine | nuclear receptor subfamily 4, group A, member 1 | Rattus norvegicus |
| 4 | Repeated L-DOPA treatment increased the striatal level of DYN mRNA but it further reduced the percentage of NGFI-B/DYN double-labeled cells. | Levodopa | nuclear receptor subfamily 4, group A, member 1 | Rattus norvegicus |
| 5 | On the intact side, repeated L-DOPA treatment increased NGFI-B expression in both striatal subpopulations. | Levodopa | nuclear receptor subfamily 4, group A, member 1 | Rattus norvegicus |
| 6 | These results demonstrate that the denervation process causes a differential regulation of NGFI-B in the two striatal output pathways which is further exacerbated by L-DOPA treatment. | Levodopa | nuclear receptor subfamily 4, group A, member 1 | Rattus norvegicus |