| Protein Name | nuclear receptor subfamily 4, group A, member 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 79240 |
| Gene Symbol | Nr4a1 |
| UniProt | P22829 (NR4A1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
133
Total Number of Articles : 135 |
Description |
nuclear receptor subfamily 4, group A, member 1 |
| Gene Summary |
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; nuclear glucocorticoid receptor binding activity; and protein heterodimerization activity. Involved in several processes, including neurotransmitter secretion involved in regulation of skeletal muscle contraction; response to amphetamine; and response to lipopolysaccharide. Predicted to be located in several cellular components, including chromatin; mitochondrion; and nucleus. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Used to study Parkinson's disease and chronic kidney disease. Biomarker of mesangial proliferative glomerulonephritis. Orthologous to human NR4A1 (nuclear receptor subfamily 4 group A member 1). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |