Title : The effects of sulphasalazine and its metabolites on prostaglandin production by human mononuclear cells.

Pub. Date : 1992 Jun 9

PMID : 1351726






2 Functional Relationships(s)
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1 Although it has been proposed that sulphasalazine (SASP) and its metabolite 5-aminosalicylic acid (5-ASA) act therapeutically by inhibiting production of vasoactive and immunoregulatory prostaglandins (PGs), in previous in vitro studies these drugs have both inhibited and promoted PG production. Mesalamine aspartic peptidase retroviral like 1 Homo sapiens
2 Although it has been proposed that sulphasalazine (SASP) and its metabolite 5-aminosalicylic acid (5-ASA) act therapeutically by inhibiting production of vasoactive and immunoregulatory prostaglandins (PGs), in previous in vitro studies these drugs have both inhibited and promoted PG production. Mesalamine aspartic peptidase retroviral like 1 Homo sapiens