Pub. Date : 1992 May
PMID : 1331428
14 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tetrodotoxin (TTX)-sensitive Ca2+ conducting channels which produce a transient inward current were investigated in pyramidal neurones freshly dissociated from the dorsal part of rat hippocampal CA1 region by the use of the suction-pipette technique, which allows for intracellular perfusion under a single-electrode voltage clamp. | Tetrodotoxin | carbonic anhydrase 2 | Rattus norvegicus |
| 2 | Tetrodotoxin (TTX)-sensitive Ca2+ conducting channels which produce a transient inward current were investigated in pyramidal neurones freshly dissociated from the dorsal part of rat hippocampal CA1 region by the use of the suction-pipette technique, which allows for intracellular perfusion under a single-electrode voltage clamp. | Tetrodotoxin | carbonic anhydrase 2 | Rattus norvegicus |
| 3 | In all cells superfused with Na(+)- and K(+)-free external solution containing 10 mM-Ca2+ and 10(-5) M-La3+, a transient inward Ca2+ current was evoked by a step depolarization to potentials more positive than about -50 mV from a holding potential (VH) of -100 mV. | lanthanum(3+) | carbonic anhydrase 2 | Rattus norvegicus |
| 4 | In all cells superfused with Na(+)- and K(+)-free external solution containing 10 mM-Ca2+ and 10(-5) M-La3+, a transient inward Ca2+ current was evoked by a step depolarization to potentials more positive than about -50 mV from a holding potential (VH) of -100 mV. | vh | carbonic anhydrase 2 | Rattus norvegicus |
| 5 | In all cells superfused with Na(+)- and K(+)-free external solution containing 10 mM-Ca2+ and 10(-5) M-La3+, a transient inward Ca2+ current was evoked by a step depolarization to potentials more positive than about -50 mV from a holding potential (VH) of -100 mV. | vh | carbonic anhydrase 2 | Rattus norvegicus |
| 6 | This current was inhibited by either removing the extracellular Ca2+ or adding TTX (termed as "TTX-ICa"). | ttx-ica | carbonic anhydrase 2 | Rattus norvegicus |
| 7 | When the peak amplitudes in the individual current-voltage (I-V) relationships of TTX-ICa at various extracellular Ca2+ concentrations ([Ca2+]o) were plotted as a function of [Ca2+]o, the current amplitude increased linearly without showing any saturation. | ttx-ica | carbonic anhydrase 2 | Rattus norvegicus |
| 8 | When the peak amplitudes in the individual current-voltage (I-V) relationships of TTX-ICa at various extracellular Ca2+ concentrations ([Ca2+]o) were plotted as a function of [Ca2+]o, the current amplitude increased linearly without showing any saturation. | ttx-ica | carbonic anhydrase 2 | Rattus norvegicus |
| 9 | When the peak amplitudes in the individual current-voltage (I-V) relationships of TTX-ICa at various extracellular Ca2+ concentrations ([Ca2+]o) were plotted as a function of [Ca2+]o, the current amplitude increased linearly without showing any saturation. | ttx-ica | carbonic anhydrase 2 | Rattus norvegicus |
| 10 | The ratio of peak amplitude in the individual I-V relationships of Ca2+, Sr2+ and Ba2+ currents passing through the TTX-sensitive Ca2+ conducting channel was 1:0.33:0.05, although the current kinetics were much the same. | strontium cation | carbonic anhydrase 2 | Rattus norvegicus |
| 11 | The ratio of peak amplitude in the individual I-V relationships of Ca2+, Sr2+ and Ba2+ currents passing through the TTX-sensitive Ca2+ conducting channel was 1:0.33:0.05, although the current kinetics were much the same. | N-methyl-valyl-amiclenomycin | carbonic anhydrase 2 | Rattus norvegicus |
| 12 | The ratio of peak amplitude in the individual I-V relationships of Ca2+, Sr2+ and Ba2+ currents passing through the TTX-sensitive Ca2+ conducting channel was 1:0.33:0.05, although the current kinetics were much the same. | N-methyl-valyl-amiclenomycin | carbonic anhydrase 2 | Rattus norvegicus |
| 13 | The ratio of peak amplitude in the individual I-V relationships of Ca2+, Sr2+ and Ba2+ currents passing through the TTX-sensitive Ca2+ conducting channel was 1:0.33:0.05, although the current kinetics were much the same. | Tetrodotoxin | carbonic anhydrase 2 | Rattus norvegicus |
| 14 | The ratio of peak amplitude in the individual I-V relationships of Ca2+, Sr2+ and Ba2+ currents passing through the TTX-sensitive Ca2+ conducting channel was 1:0.33:0.05, although the current kinetics were much the same. | Tetrodotoxin | carbonic anhydrase 2 | Rattus norvegicus |