Title : Acute and chronic effects of angiotensin-converting enzyme inhibitors on tissue angiotensin-converting enzyme.

Pub. Date : 1992

PMID : 1327597






4 Functional Relationships(s)
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1 Following acute administration of lisinopril, perindopril or benazepril, ACE was markedly inhibited in the lung, kidney and blood vessels but not in the testis. Lisinopril angiotensin I converting enzyme Homo sapiens
2 After chronic administration of lisinopril or perindopril for 14 days, a similar pattern of ACE inhibition was observed in the kidney, lung and blood vessels. Lisinopril angiotensin I converting enzyme Homo sapiens
3 In the lung, however, lisinopril was found to increase total ACE by 30%, while plasma ACE was increased two-threefold by both lisinopril and perindopril. Lisinopril angiotensin I converting enzyme Homo sapiens
4 In the lung, however, lisinopril was found to increase total ACE by 30%, while plasma ACE was increased two-threefold by both lisinopril and perindopril. Lisinopril angiotensin I converting enzyme Homo sapiens