Title : Endothelin vascular receptors and responses in deoxycorticosterone acetate-salt hypertensive rats.

Pub. Date : 1992 Feb

PMID : 1310486






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Binding of ET-1 to mesenteric artery membranes was significantly lower in DOCA-salt rats (106 +/- 22 fmol/mg protein) than in uninephrectomized rats (172 +/- 19 fmol/mg protein, p less than 0.05), whereas affinity was similar. Desoxycorticosterone Acetate endothelin 1 Rattus norvegicus
2 In conclusion, decreased density of ET-1 receptors in DOCA-salt hypertensive rats results in decreased activation of phospholipase C and, consequently, reduced vasoconstriction induced by ET-1. Desoxycorticosterone Acetate endothelin 1 Rattus norvegicus
3 In conclusion, decreased density of ET-1 receptors in DOCA-salt hypertensive rats results in decreased activation of phospholipase C and, consequently, reduced vasoconstriction induced by ET-1. Desoxycorticosterone Acetate endothelin 1 Rattus norvegicus