Title : The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity.

Pub. Date : 2003 Jul

PMID : 12819769






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 The cell death-inducing serine protease granzyme A (GzmA) has a unique disulfide-linked quaternary structure. Disulfides granzyme A Homo sapiens
2 The cell death-inducing serine protease granzyme A (GzmA) has a unique disulfide-linked quaternary structure. Disulfides granzyme A Homo sapiens
3 The structure of human GzmA bound to a tripeptide CMK inhibitor, determined at a resolution of 2.4 A, reveals that the oligomeric state contributes to substrate selection by limiting access to the active site for potential macromolecular substrates and inhibitors. tripeptide K-26 granzyme A Homo sapiens