Pub. Date : 1992 Dec
PMID : 1281562
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The damage induced by FK506 and CsA was characterized by a direct cytotoxic effect on tubular cells, as expressed by release of 3H thymidine from prelabeled cells, N-acetyl-beta-D-glucosaminidase release, and cell detachment. | Cyclosporine | O-GlcNAcase | Rattus norvegicus |
| 2 | CsA 10, 1, 0.1, 0.01 also exerted an enhancing effect on ET-1 secretion in cultured tubular cells. | Cyclosporine | endothelin 1 | Rattus norvegicus |
| 3 | The concentrations of FK506 or CsA that induced ET-1 secretion were not cytolytic for tubular cells in vitro. | Cyclosporine | endothelin 1 | Rattus norvegicus |
| 4 | FK506- or CsA-treated rats showed an increase in serum level of ET-1 in comparison with the control. | Cyclosporine | endothelin 1 | Rattus norvegicus |