| Protein Name | glutamate receptor, ionotropic, kainate 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 14805 |
| Gene Symbol | Grik1 |
| UniProt | Q3UZT1 (Q3UZT1_MOUSE), A0A2I3BQM2 (A0A2I3BQM2_MOUSE), A0A2I3BPT2 (A0A2I3BPT2_MOUSE), Q8BRT2 (Q8BRT2_MOUSE), Q8BQZ0 (Q8BQZ0_MOUSE), Q8C825 (Q8C825_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
598
Total Number of Articles : 1165 |
Description |
glutamate receptor, ionotropic, kainate 1 |
| Gene Summary |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008] |
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