Title : A naturally occurring mutation in an ATP-binding domain of the recombination repair gene XRCC3 ablates its function without causing cancer susceptibility.

Pub. Date : 2003 Apr 15

PMID : 12668615






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A naturally occurring mutation in an ATP-binding domain of the recombination repair gene XRCC3 ablates its function without causing cancer susceptibility. Adenosine Triphosphate X-ray repair cross complementing 3 Homo sapiens
2 One of these variants, D213N, occurs in a highly conserved ATP-binding domain and completely abrogates the ability of the transfected gene to correct the phenotype of XRCC3 deficient cells. Adenosine Triphosphate X-ray repair cross complementing 3 Homo sapiens