Title : Ligation of retinoic acid receptor alpha regulates negative selection of thymocytes by inhibiting both DNA binding of nur77 and synthesis of bim.

Pub. Date : 2003 Apr 1

PMID : 12646620






1 Functional Relationships(s)
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1 Ligation of RARalpha by the synthetic agonist CD336 inhibited apoptosis, DNA binding of nur77, and synthesis of bim induced by anti-CD3 or the specific Ag, but had no effect on the superantigen-driven cell death. Am 580 nuclear receptor subfamily 4, group A, member 1 Mus musculus