| Protein Name | nuclear receptor subfamily 4, group A, member 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 15370 |
| Gene Symbol | Nr4a1 |
| UniProt | P12813 (NR4A1_MOUSE), Q545Q1 (Q545Q1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
239
Total Number of Articles : 241 |
Description |
nuclear receptor subfamily 4, group A, member 1 |
| Gene Summary |
Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and lipopolysaccharide binding activity. Involved in several processes, including cellular response to corticotropin-releasing hormone stimulus; detection of lipopolysaccharide; and non-canonical inflammasome complex assembly. Acts upstream of or within several processes, including macrophage activation; protein import into nucleus; and skeletal muscle cell differentiation. Located in chromatin; cytosol; and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; clavicle; genitourinary system; hemolymphoid system; and nervous system. Orthologous to human NR4A1 (nuclear receptor subfamily 4 group A member 1). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |