Title : Powering the peptide pump: TAP crosstalk with energetic nucleotides.

Pub. Date : 2002 Sep

PMID : 12217520






1 Functional Relationships(s)
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1 In this opinion article, a model of alternating ATP binding and hydrolysis is proposed, in which nucleotide interaction with TAP2 primarily controls substrate binding and release, whereas interaction with TAP1 controls structural rearrangements of the transmembrane pathway. Adenosine Triphosphate transporter 1, ATP binding cassette subfamily B member Homo sapiens