CPRiL

TAP1

transporter 1, ATP binding cassette subfamily B member

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

• antigen peptide transporter 1
• ABC transporter, MHC 1
• ATP-binding cassette sub-family B member 2
ATP-binding cassette, sub-family B (MDR/TAP), member 2
peptide supply factor 1
peptide transporter PSF1
peptide transporter TAP1
peptide transporter involved in antigen processing 1
really interesting new gene 4 protein
transporter 1 ATP-binding cassette sub-family B
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
transporter associated with antigen processing
transporter, ATP-binding cassette, major histocompatibility complex, 1
ABC17
ABCB2
APT1
D6S114E
MHC1D1
PSF-1
PSF1
RING4
TAP1*0102N
TAP1N