Title : LAG1 puts the focus on ceramide signaling.

Pub. Date : 2002 Nov

PMID : 12200041






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 LAG1 puts the focus on ceramide signaling. Ceramides sphingosine N-acyltransferase LAG1 Saccharomyces cerevisiae S288C
2 The Lag 1 protein is located in the endoplasmic reticulum (ER), where it helps to accelerate the transport of glycosylphosphatidylinositol (GPI)-anchored proteins to the Golgi. Glycosylphosphatidylinositols sphingosine N-acyltransferase LAG1 Saccharomyces cerevisiae S288C
3 The Lag 1 protein is located in the endoplasmic reticulum (ER), where it helps to accelerate the transport of glycosylphosphatidylinositol (GPI)-anchored proteins to the Golgi. Glycosylphosphatidylinositols sphingosine N-acyltransferase LAG1 Saccharomyces cerevisiae S288C
4 This function of Lag 1 p results from its participation in ceramide synthesis. Ceramides sphingosine N-acyltransferase LAG1 Saccharomyces cerevisiae S288C
5 Thus, Lag 1 p and its homologues are likely to play a role in ceramide signaling, which affects growth, proliferation, stress resistance, and apoptosis. Ceramides sphingosine N-acyltransferase LAG1 Saccharomyces cerevisiae S288C