Pub. Date : 2002 Nov 1
PMID : 12196518
13 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Calmodulin modulates the delay period between release of calcium from internal stores and activation of calcium influx via endogenous TRP1 channels. | Calcium | LOC100759184 | Cricetulus griseus |
| 2 | Calmodulin modulates the delay period between release of calcium from internal stores and activation of calcium influx via endogenous TRP1 channels. | Calcium | LOC100759184 | Cricetulus griseus |
| 3 | In the present study we have explored the role of calmodulin (CaM) and inositol 1,4,5-trisphosphate receptor (IP(3)R) in the communication process activated after the release of calcium from the endoplasmic reticulum (ER) and the activation of calcium influx via endogenous TRP1 channels from Chinese hamster ovary cells. | Calcium | LOC100759184 | Cricetulus griseus |
| 4 | In the present study we have explored the role of calmodulin (CaM) and inositol 1,4,5-trisphosphate receptor (IP(3)R) in the communication process activated after the release of calcium from the endoplasmic reticulum (ER) and the activation of calcium influx via endogenous TRP1 channels from Chinese hamster ovary cells. | Calcium | LOC100759184 | Cricetulus griseus |
| 5 | In the present study we have explored the role of calmodulin (CaM) and inositol 1,4,5-trisphosphate receptor (IP(3)R) in the communication process activated after the release of calcium from the endoplasmic reticulum (ER) and the activation of calcium influx via endogenous TRP1 channels from Chinese hamster ovary cells. | Calcium | LOC100759184 | Cricetulus griseus |
| 6 | Furthermore, the use of selective CaM antagonists W7 and trifluoperazine maleate resulted in a substantial reduction of the delay period to 200 +/- 100 ms with 5 microm trifluoperazine maleate (n = 16) and 150 +/- 50 ms with 500 nm W7 (n = 22). | W 7 | LOC100759184 | Cricetulus griseus |
| 7 | Furthermore, the use of selective CaM antagonists W7 and trifluoperazine maleate resulted in a substantial reduction of the delay period to 200 +/- 100 ms with 5 microm trifluoperazine maleate (n = 16) and 150 +/- 50 ms with 500 nm W7 (n = 22). | trifluoperazine dimaleate | LOC100759184 | Cricetulus griseus |
| 8 | Furthermore, the use of selective CaM antagonists W7 and trifluoperazine maleate resulted in a substantial reduction of the delay period to 200 +/- 100 ms with 5 microm trifluoperazine maleate (n = 16) and 150 +/- 50 ms with 500 nm W7 (n = 22). | trifluoperazine dimaleate | LOC100759184 | Cricetulus griseus |
| 9 | CaM reduced also the current density activated by thapsigargin or brandykinin to about 60% from control. | Thapsigargin | LOC100759184 | Cricetulus griseus |
| 10 | CaM reduced also the current density activated by thapsigargin or brandykinin to about 60% from control. | brandykinin | LOC100759184 | Cricetulus griseus |
| 11 | The results presented here are consistent with an antagonistic effect of IP(3)R and CaM for the activation of store operated calcium after depletion of the ER. | Calcium | LOC100759184 | Cricetulus griseus |
| 12 | The functional competition between the activating effect of IP(3)R and the inhibiting effect of CaM may modulate the delay period between the release of calcium from the ER and the activation of calcium influx observed in different cells, as well as the amount of current activated after depletion of the ER. | Calcium | LOC100759184 | Cricetulus griseus |
| 13 | The functional competition between the activating effect of IP(3)R and the inhibiting effect of CaM may modulate the delay period between the release of calcium from the ER and the activation of calcium influx observed in different cells, as well as the amount of current activated after depletion of the ER. | Calcium | LOC100759184 | Cricetulus griseus |