PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12196518-0 2002 Calmodulin modulates the delay period between release of calcium from internal stores and activation of calcium influx via endogenous TRP1 channels. Calcium 57-64 LOC100759184 Cricetulus griseus 0-10 12196518-0 2002 Calmodulin modulates the delay period between release of calcium from internal stores and activation of calcium influx via endogenous TRP1 channels. Calcium 57-64 short transient receptor potential channel 1 Cricetulus griseus 134-138 12196518-0 2002 Calmodulin modulates the delay period between release of calcium from internal stores and activation of calcium influx via endogenous TRP1 channels. Calcium 104-111 LOC100759184 Cricetulus griseus 0-10 12196518-0 2002 Calmodulin modulates the delay period between release of calcium from internal stores and activation of calcium influx via endogenous TRP1 channels. Calcium 104-111 short transient receptor potential channel 1 Cricetulus griseus 134-138 12196518-1 2002 In the present study we have explored the role of calmodulin (CaM) and inositol 1,4,5-trisphosphate receptor (IP(3)R) in the communication process activated after the release of calcium from the endoplasmic reticulum (ER) and the activation of calcium influx via endogenous TRP1 channels from Chinese hamster ovary cells. Calcium 178-185 LOC100759184 Cricetulus griseus 50-60 12196518-1 2002 In the present study we have explored the role of calmodulin (CaM) and inositol 1,4,5-trisphosphate receptor (IP(3)R) in the communication process activated after the release of calcium from the endoplasmic reticulum (ER) and the activation of calcium influx via endogenous TRP1 channels from Chinese hamster ovary cells. Calcium 178-185 LOC100759184 Cricetulus griseus 62-65 12196518-1 2002 In the present study we have explored the role of calmodulin (CaM) and inositol 1,4,5-trisphosphate receptor (IP(3)R) in the communication process activated after the release of calcium from the endoplasmic reticulum (ER) and the activation of calcium influx via endogenous TRP1 channels from Chinese hamster ovary cells. Calcium 244-251 LOC100759184 Cricetulus griseus 50-60 12196518-6 2002 Furthermore, the use of selective CaM antagonists W7 and trifluoperazine maleate resulted in a substantial reduction of the delay period to 200 +/- 100 ms with 5 microm trifluoperazine maleate (n = 16) and 150 +/- 50 ms with 500 nm W7 (n = 22). W 7 50-52 LOC100759184 Cricetulus griseus 34-37 12196518-6 2002 Furthermore, the use of selective CaM antagonists W7 and trifluoperazine maleate resulted in a substantial reduction of the delay period to 200 +/- 100 ms with 5 microm trifluoperazine maleate (n = 16) and 150 +/- 50 ms with 500 nm W7 (n = 22). trifluoperazine dimaleate 57-80 LOC100759184 Cricetulus griseus 34-37 12196518-6 2002 Furthermore, the use of selective CaM antagonists W7 and trifluoperazine maleate resulted in a substantial reduction of the delay period to 200 +/- 100 ms with 5 microm trifluoperazine maleate (n = 16) and 150 +/- 50 ms with 500 nm W7 (n = 22). trifluoperazine dimaleate 169-192 LOC100759184 Cricetulus griseus 34-37 12196518-7 2002 CaM reduced also the current density activated by thapsigargin or brandykinin to about 60% from control. Thapsigargin 50-62 LOC100759184 Cricetulus griseus 0-3 12196518-7 2002 CaM reduced also the current density activated by thapsigargin or brandykinin to about 60% from control. brandykinin 66-77 LOC100759184 Cricetulus griseus 0-3 12196518-9 2002 The results presented here are consistent with an antagonistic effect of IP(3)R and CaM for the activation of store operated calcium after depletion of the ER. Calcium 125-132 LOC100759184 Cricetulus griseus 84-87 12196518-10 2002 The functional competition between the activating effect of IP(3)R and the inhibiting effect of CaM may modulate the delay period between the release of calcium from the ER and the activation of calcium influx observed in different cells, as well as the amount of current activated after depletion of the ER. Calcium 153-160 LOC100759184 Cricetulus griseus 96-99 12196518-10 2002 The functional competition between the activating effect of IP(3)R and the inhibiting effect of CaM may modulate the delay period between the release of calcium from the ER and the activation of calcium influx observed in different cells, as well as the amount of current activated after depletion of the ER. Calcium 195-202 LOC100759184 Cricetulus griseus 96-99