Title : Active site residues of cyclophilin A are crucial for its signaling activity via CD147.

Pub. Date : 2002 Jun 21

PMID : 11943775






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cyclophilin A (CyPA), a ubiquitously distributed intracellular protein, is a peptidylprolyl cis-trans-isomerase and the major target of the potent immunosuppressive drug cyclosporin A. Cyclosporine peptidylprolyl isomerase A Homo sapiens
2 Cyclophilin A (CyPA), a ubiquitously distributed intracellular protein, is a peptidylprolyl cis-trans-isomerase and the major target of the potent immunosuppressive drug cyclosporin A. Cyclosporine peptidylprolyl isomerase A Homo sapiens
3 Both signaling and chemotactic activities of CyPA depended also on the presence of heparans, which served as primary binding sites for CyPA on target cells. heparans peptidylprolyl isomerase A Homo sapiens
4 Both signaling and chemotactic activities of CyPA depended also on the presence of heparans, which served as primary binding sites for CyPA on target cells. heparans peptidylprolyl isomerase A Homo sapiens