Title : [Expression of matrix metalloproteinase-2 in rat pulmonary fibrosis].

Pub. Date : 2001 Dec

PMID : 11866990






3 Functional Relationships(s)
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1 METHODS: (1) Dynamic changes of MMP(2) expression were observed in bleomycin-induced rat pulmonary fibrosis by use of immunohistochemical technique. Bleomycin matrix metallopeptidase 2 Rattus norvegicus
2 RESULTS: (1) On day 1-7th after receiving bleomycin, the infiltrated pulmonary macrophages and septa mesenchymal cells showed positive reaction with anti-MMP(2) and an increase in number. Bleomycin matrix metallopeptidase 2 Rattus norvegicus
3 (2) The gene expression of MMP(2) mRNA of PFbs were enhanced after bleomycin treatment from the Day 1 and decreased by Day 28. Bleomycin matrix metallopeptidase 2 Rattus norvegicus