Title : The tyrosine motifs of Lamp 1 and LAP determine their direct and indirect targetting to lysosomes.

Pub. Date : 2002 Jan 1

PMID : 11801736






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The tyrosine motifs of Lamp 1 and LAP determine their direct and indirect targetting to lysosomes. Tyrosine acid phosphatase 2, lysosomal Homo sapiens
2 Lamp 1 and lysosomal acid phosphatase (LAP) are lysosomal membrane proteins that harbour a tyrosine-based sorting motif within their short cytoplasmic tails. Tyrosine acid phosphatase 2, lysosomal Homo sapiens
3 Lamp 1 and lysosomal acid phosphatase (LAP) are lysosomal membrane proteins that harbour a tyrosine-based sorting motif within their short cytoplasmic tails. Tyrosine acid phosphatase 2, lysosomal Homo sapiens
4 In conclusion, the residues +2 and +3 of the tyrosine motifs determine the sorting of Lamp 1 and LAP in endosomes, mediating either the direct or the indirect pathway to lysosomes. Tyrosine acid phosphatase 2, lysosomal Homo sapiens