Pub. Date : 2001 Dec 1
PMID : 11784055
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rapamycin, a specific inhibitor of the kinase mTOR/FRAP/RAFT1, blocks amino acid stimulation of embryo outgrowth, demonstrating that mTOR is required for the initiation of trophectoderm protrusive activity. | Sirolimus | mechanistic target of rapamycin kinase | Mus musculus |
| 2 | Rapamycin, a specific inhibitor of the kinase mTOR/FRAP/RAFT1, blocks amino acid stimulation of embryo outgrowth, demonstrating that mTOR is required for the initiation of trophectoderm protrusive activity. | Sirolimus | mechanistic target of rapamycin kinase | Mus musculus |
| 3 | Rapamycin, a specific inhibitor of the kinase mTOR/FRAP/RAFT1, blocks amino acid stimulation of embryo outgrowth, demonstrating that mTOR is required for the initiation of trophectoderm protrusive activity. | Sirolimus | mechanistic target of rapamycin kinase | Mus musculus |
| 4 | Rapamycin, a specific inhibitor of the kinase mTOR/FRAP/RAFT1, blocks amino acid stimulation of embryo outgrowth, demonstrating that mTOR is required for the initiation of trophectoderm protrusive activity. | Sirolimus | mechanistic target of rapamycin kinase | Mus musculus |
| 5 | Inhibition of global protein translation with cycloheximide also inhibits amino acid-dependent signals, suggesting that mTOR regulates the translation of proteins required for trophoblast differentiation. | Cycloheximide | mechanistic target of rapamycin kinase | Mus musculus |