Title : Peroxynitrite-induced myocardial injury is mediated through matrix metalloproteinase-2.

Pub. Date : 2002 Jan

PMID : 11744025






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Peroxynitrite-induced myocardial injury is mediated through matrix metalloproteinase-2. Peroxynitrous Acid matrix metallopeptidase 2 Rattus norvegicus
2 The MMPs inhibitor PD-166793 prevented the ONOO(-)-induced loss in myocardial mechanical function. (R)-2-(4'-bromo-biphenyl-4-sulfonyl-amino)-3-methyl-butyric acid matrix metallopeptidase 2 Rattus norvegicus
3 The MMPs inhibitor PD-166793 prevented the ONOO(-)-induced loss in myocardial mechanical function. onoo(-) matrix metallopeptidase 2 Rattus norvegicus
4 CONCLUSIONS: Acute cardiac toxicity induced by ONOO(-) is mediated by MMP-2. onoo(-) matrix metallopeptidase 2 Rattus norvegicus