Title : Discovery of a series of nonpeptide small molecules that inhibit the binding of insulin-like growth factor (IGF) to IGF-binding proteins.

Pub. Date : 2001 Nov 8

PMID : 11689087






2 Functional Relationships(s)
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1 Here we report the discovery of several isoquinoline analogues, exemplified by 1 and 2, which bind IGFBP-3 as well as other IGFBPs at low nanomolar concentrations. isoquinoline insulin like growth factor binding protein 3 Homo sapiens
2 Here we report the discovery of several isoquinoline analogues, exemplified by 1 and 2, which bind IGFBP-3 as well as other IGFBPs at low nanomolar concentrations. isoquinoline insulin like growth factor binding protein 3 Homo sapiens