Title : Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP3A4 enzymes.

Pub. Date : 2001 Oct

PMID : 11560868






1 Functional Relationships(s)
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1 Two enantiomers, (+)- and (-)-9-hydroxyrisperidone might be formed, and the aim of this study was to evaluate the importance of CYP2D6 and CYP3A4/CYP3A5 in the formation of these two enantiomers in human liver microsomes and in recombinantly expressed enzymes. Paliperidone Palmitate cytochrome P450 family 3 subfamily A member 5 Homo sapiens