Pub. Date : 2001 May 31
PMID : 11397554
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Microcystin-induced down-regulation of lymphocyte functions through reduced IL-2 mRNA stability. | microcystin | interleukin 2 | Mus musculus |
| 2 | Deprivation of PMA/ionomycin stimuli from activated splenocytes and blockade of new transcription resulted in destabilization of IL-2 mRNA, which was accelerated by MC treatment. | microcystin | interleukin 2 | Mus musculus |
| 3 | These results demonstrated that MC down-regulated lymphocyte functions and the immunosuppression was mediated, at least in part, through decreased IL-2 mRNA stability. | microcystin | interleukin 2 | Mus musculus |