Title : Sanglifehrin A, a novel cyclophilin-binding compound showing immunosuppressive activity with a new mechanism of action.

Pub. Date : 2001 Jun 15

PMID : 11390463






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 SFA is a representative of a class of macrolides produced by actinomycetes that bind to cyclophilin A (CypA), the binding protein of the fungal cyclic peptide cyclosporin A (CsA). sanglifehrin A peptidylprolyl isomerase A Homo sapiens
2 SFA is a representative of a class of macrolides produced by actinomycetes that bind to cyclophilin A (CypA), the binding protein of the fungal cyclic peptide cyclosporin A (CsA). sanglifehrin A peptidylprolyl isomerase A Homo sapiens
3 SFA is a representative of a class of macrolides produced by actinomycetes that bind to cyclophilin A (CypA), the binding protein of the fungal cyclic peptide cyclosporin A (CsA). Macrolides peptidylprolyl isomerase A Homo sapiens
4 SFA is a representative of a class of macrolides produced by actinomycetes that bind to cyclophilin A (CypA), the binding protein of the fungal cyclic peptide cyclosporin A (CsA). Macrolides peptidylprolyl isomerase A Homo sapiens
5 SFA interacts with high affinity with the CsA binding side of CypA and inhibits its peptidyl-prolyl isomerase activity. Cyclosporine peptidylprolyl isomerase A Homo sapiens