Pub. Date : 1998 Dec
PMID : 11367673
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The main results are as follows: (1) under normoxia both ACE activity and gene expression could be detected in PASMC; and (2) the expression level of ACE mRNA, after an initial latent period of 6 h hypoxia, began to show a marked increase with time in the next 12, 24 and 48 h. Exposure to hypoxia for 24 h resulted in an increase in either culture medium or cell ACE activity, as compared with that under normoxia. | pasmc | angiotensin-converting enzyme | Oryctolagus cuniculus |
| 2 | The results suggest that PASMC ACE increased by hypoxia might play an important role in the development of hypoxic pulmonary hypertension. | pasmc | angiotensin-converting enzyme | Oryctolagus cuniculus |