PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11367673-2 1998 The main results are as follows: (1) under normoxia both ACE activity and gene expression could be detected in PASMC; and (2) the expression level of ACE mRNA, after an initial latent period of 6 h hypoxia, began to show a marked increase with time in the next 12, 24 and 48 h. Exposure to hypoxia for 24 h resulted in an increase in either culture medium or cell ACE activity, as compared with that under normoxia. pasmc 111-116 angiotensin-converting enzyme Oryctolagus cuniculus 57-60 11367673-3 1998 The results suggest that PASMC ACE increased by hypoxia might play an important role in the development of hypoxic pulmonary hypertension. pasmc 25-30 angiotensin-converting enzyme Oryctolagus cuniculus 31-34