Pub. Date : 2001 May
PMID : 11312344
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we show that while CyP A binds both Gag and mature CA proteins, the two binding interactions are actually different. | Glycosaminoglycans | peptidylprolyl isomerase A | Homo sapiens |
| 2 | Tryptophan 121 (W121) in CyP A distinguished the two proteins: a phenylalanine substitution (W121F) impaired binding of mature CA protein but not of Gag. | Tryptophan | peptidylprolyl isomerase A | Homo sapiens |
| 3 | Tryptophan 121 (W121) in CyP A distinguished the two proteins: a phenylalanine substitution (W121F) impaired binding of mature CA protein but not of Gag. | Phenylalanine | peptidylprolyl isomerase A | Homo sapiens |
| 4 | A structural consequence of Gag binding to CyP A was to block this maturational refolding, resulting in a 24-kDa CA protein retaining the immature Pro-rich loop conformation. | Glycosaminoglycans | peptidylprolyl isomerase A | Homo sapiens |
| 5 | Binding to wild-type CyP A altered this conformation, as indicated by a reduction in the accessibility of Cys residue(s) in the region to chemical modification. | Cysteine | peptidylprolyl isomerase A | Homo sapiens |