Pub. Date : 2001 May 25
PMID : 11279134
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment of these MIX-deficient cells with a PPARgamma ligand, troglitazone, induces C/EBPalpha expression and rescues the block in adipogenesis. | Troglitazone | CCAAT/enhancer binding protein (C/EBP), alpha | Mus musculus |
| 2 | In this regard, we also show that induction of C/EBPalpha gene expression by troglitazone in C3H10T1/2 cells ectopically expressing PPARgamma occurs in the absence of ongoing protein synthesis, suggesting a direct transactivation of the C/EBPalpha gene by PPARgamma. | Troglitazone | CCAAT/enhancer binding protein (C/EBP), alpha | Mus musculus |
| 3 | In this regard, we also show that induction of C/EBPalpha gene expression by troglitazone in C3H10T1/2 cells ectopically expressing PPARgamma occurs in the absence of ongoing protein synthesis, suggesting a direct transactivation of the C/EBPalpha gene by PPARgamma. | Troglitazone | CCAAT/enhancer binding protein (C/EBP), alpha | Mus musculus |
| 4 | Additionally, we show that sustained expression of C/EBPalpha in these LIP-expressing adipocytes requires constant exposure to troglitazone. | Troglitazone | CCAAT/enhancer binding protein (C/EBP), alpha | Mus musculus |